Get Rid of Large Pores and Blemishes - 1) Mix equal parts baking soda and warm water (2 tablespoons each) into a paste. 2) Using a circular motion, massage paste into pores gently for about 30 seconds. 3) Rinse off using cool water. 4) Use this regimen as part of your normal face-washing routine, every night, for 5 to 7 days. After a week of use, reduce regimen to 3 to 5 times per week.