Our poor doggie! He got sprayed by a nasty skunk! This happened to us about 10 months ago while I was pregnant! It was awful. Both times now, I have hooked up the diffusers right away with Citrus Bliss, Purify and Grapefruit. I use a hefty dose, so about 8 drops of each in the diffuser and then run for 4 hours. This works amazingly for the difficult to remove skunk smells from the house.TOXIN FREE and all natural.