NO. The other two didn't get all moody and angry when the third person was holding the locket. The ring damaged Dumbledore because it was cursed and poisoned him, not because of a horcrux. The only person this would affect is HARRY because he freaking WAS the horcrux, that's why he's so moody and obnoxious half the time!! The Dursleys were just horrible people, no excuses.